Want to join our team? We’ve got a PhD research fellowship position currently open, please find the details below.
Take a look also at our open Post-doc fellow/researcher position.
About the position
This is a three-year, full-time position on a Research Fellowship as a PhD Candidate here at the Haapaniemi Group, based at NCMM, University of Oslo & Oslo University Hospital.
The research fellow will take part in an approved PhD program at the University of Oslo and is expected to complete the project within the set fellowship period. The main purpose of the fellowship is research training leading to the successful completion of a PhD degree.
The successful candidate will join a highly integrated and motivated team with diverse skills and expertise across molecular biology and immunology.
Our team works towards building a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases.
We use high-throughput biology techniques to optimise, develop and understand the CRISPR-Cas9 system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the gene editing technologies for the benefit of the patients in the Nordic hospitals.
NCMM was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway, and has altogether 11 research groups.
The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.
Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year.
The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence.
Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.
The work tasks will be tailored based on the candidate’s interests, and will concentrate on optimising and scaling up protocols for efficient mutation correction in human T cells and hematopoietic stem cells.
Examples of work tasks include:
- Optimise T cell and stem cell ex vivo editing & culturing conditions
- Transplant edited cells to humanised mice
- Design and optimise high-throughput biology experiments in robotics platforms
- Set up custom Next Generation Sequencing libraries and technologies
- Scale up protocols to pre-GMP and GMP scale
Required qualifications & skills
- Master’s degree or equivalent in life sciences
- Experience in multiple academic or private research environments
- Proven expertise in immunology, primary cell culture or Next Generation Sequencing library design
- Fluent oral and written communication skills in English
- Highly motivated and structured, enthusiastic and hardworking
What we offer
Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.
How to apply?
Your application must include:
- Cover letter (statement of motivation, summarizing scientific work and research interest)
- CV summarizing education, positions, and other qualifying activity
- List of publications
- Copies of educational certificates (academic transcripts only)
- List of 3 reference persons (name, relation to candidate, e-mail and phone number)