Our team
September 22, 2022
About us
Our focus
Our group focuses on developing targeted therapies for rare immunological conditions, such as primary immunodeficiency diseases and immunological conditions of unknown origin.
Our aim
We aim to optimize the CRISPR-Cas gene editing technology as a gene therapy in these diseases, and stratify the existing therapies – such as biologic drugs and small molecule inhibitors – to better target the underlying molecular pathways that malfunction in individual patients.
Our methods
We utilise custom genomics and high-throughput screening to understand immune diseases and optimize CRISPR-Cas9 genome editing towards safe and efficient use in patients. We work with cell models and patient material.
Our team
Our international team is based at the Centre for Molecular Medicine Norway in Oslo, Norway. We have diverse backgrounds and expertise in biosciences and clinical medicine.
Our research
Our main projects involve optimising genome editing, along with personalised use of targeted therapies in rare diseases. We’re interested in rare and undiagnosed immunological diseases.
Publications
See our latest studies and research highlights in genome editing and novel genetic etiologies of immunological diseases in chronological order.
Latest news
Research and publications
We’ve won the European Genomics Grant
We’ve won the European Genomics Grant from Standard BioTools! As the prize we will have the C1 system from Standard BioTools™ installed in our laboratory.
July 27, 2022
Our team
Jacob’s master’s thesis defense and new role at Haapaniemi group
On 22nd of June, Jacob defended his master thesis “In vivo and in vitro strategies to study precise gene editing using CRISPR-Cas9”.
July 26, 2022
Who supports us?
Centre for Molecular Medicine Norway
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The Research Council of Norway
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Norwegian Cancer Society
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South-Eastern Norway Regional Health Authority
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Oslo University Hospital
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The Swedish Childhood Cancer Fund
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Academy of Finland
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Instrumentarium Science Foundation
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