Our team
January team changes
Thapelo is back with us to work on his master’s thesis, and Carolina has joined the team as our new PhD student. Welcome!
January 30, 2023
About us
Our focus
Our group focuses on developing targeted therapies for rare immunological conditions, such as primary immunodeficiency diseases and immunological conditions of unknown origin.
Our aim
We aim to optimize the CRISPR-Cas gene editing technology as a gene therapy in these diseases, and stratify the existing therapies – such as biologic drugs and small molecule inhibitors – to better target the underlying molecular pathways that malfunction in individual patients.
Our methods
We utilise custom genomics and high-throughput screening to understand immune diseases and optimize CRISPR-Cas9 genome editing towards safe and efficient use in patients. We work with cell models and patient material.
Our team
Our international team is based at the Centre for Molecular Medicine Norway in Oslo, Norway. We have diverse backgrounds and expertise in biosciences and clinical medicine.
Our research
Our main projects involve optimising genome editing, along with personalised use of targeted therapies in rare diseases. We’re interested in rare and undiagnosed immunological diseases.
Publications
See our latest studies and research highlights in genome editing and novel genetic etiologies of immunological diseases in chronological order.
Latest news
Lab updates
PRIMA, a new Center of Excellence received funding!
We are very proud to be part of Precision Immunotherapy Alliance “PRIMA”, a new Center of Excellence recently founded by The Research Council of Norway!
September 30, 2022
Our team
September 22, 2022
Who supports us?
Centre for Molecular Medicine Norway
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The Research Council of Norway
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Norwegian Cancer Society
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South-Eastern Norway Regional Health Authority
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Oslo University Hospital
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The Swedish Childhood Cancer Fund
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Academy of Finland
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Instrumentarium Science Foundation
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