Our group focuses on developing targeted therapies for rare immunological conditions, such as primary immunodeficiency diseases and immunological conditions of unknown origin.
We aim to optimize the CRISPR-Cas gene editing technology as a gene therapy in these diseases, and stratify the existing therapies – such as biologic drugs and small molecule inhibitors – to better target the underlying molecular pathways that malfunction in individual patients.
We utilise custom genomics and high-throughput screening to understand immune diseases and optimize CRISPR-Cas9 genome editing towards safe and efficient use in patients. We work with cell models and patient material.
Our international team is based at the Centre for Molecular Medicine Norway in Oslo, Norway. We have diverse backgrounds and expertise in biosciences and clinical medicine.
Our main projects involve optimising genome editing, along with personalised use of targeted therapies in rare diseases. We’re interested in rare and undiagnosed immunological diseases.
See our latest studies and research highlights in genome editing and novel genetic etiologies of immunological diseases in chronological order.
Our group had an open position for a 3-year PhD research fellow
The 3-day winter retreat took place at the Dr. Holms hotel in Geilo, Norway.
This collaborative grant will enable our work towards developing innovative nanotechnology-based systems to support stem cell viability and advance gene editing therapies.
We are proud to be a part of the new Centre of Excellence: The Precision Immunotherapy Alliance (PRIMA).