News

[Closed] Postdoctoral fellow/researcher position open at Haapaniemi Lab

Please note, application deadline has now passed.

Thank you to everyone who applied! Keep an eye out in the News for any future open positions in our group.

Our group is growing again! In addition to a researcher position, we’re happy to also announce that we have a position open for a postdoctoral fellow/researcher at our lab.

Please find the related information below, and do get in touch if you’re interested in this position or would like any further details. 😊

About the position

This is a three-year research position in our CRISPR gene therapy group led by Emma Haapaniemi to be based at our lab located at NCMM, University of Oslo & Oslo University Hospital.

We welcome applications both from recent PhD graduates (postdoctoral fellow position) and more experienced scientists (researcher position).

Our team works towards building a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases.

We use high-throughput biology techniques to optimise, develop and understand the CRISPR-Cas9 system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the gene editing technologies for the benefit of the patients in the Nordic hospitals.

NCMM was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway, and has altogether 11 research groups.

The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year.

The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence.

Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.

Work tasks

We are primarily looking for an experienced scientist with competence in basic stem cell research to support the work on hematopoietic stem cell gene editing & protocol scale-up.

Examples of work tasks include:

  • Optimise stem cell ex vivo editing & culturing conditions
  • Characterise the functionality of the edited stem cells in vitro
  • Transplant edited cells to humanised mice
  • Design and optimise high-throughput biology experiments in robotics platforms
  • Set up custom Next Generation Sequencing libraries and technologies
  • Scale up protocols to pre-GMP and GMP scale

Required qualifications

  • PhD, BA or MA (expected PhD graduation date within 6 months of application closing date)
  • At least one published first-author paper
  • Fluent oral and written English communication skills
The following qualifications will count in the assessment of the applicants:
  • Documented experience in (hematopoietic) stem cell research
  • Experience with any of the following techniques: multi-color flow cytometry, Next Generation Sequencing library preparation, immune cell culture and transfection
  • CRISPR editing in primary cells, or experience with human-mouse xenotransplants
  • Experience in genetic analyses
  • Ability to communicate and work in shared multidisciplinary projects
  • Experience in student supervision

Required personal skills and qualities

  • Good communications and interpersonal skills
  • Adaptability and flexibility
  • Highly motivated
  • Goal-oriented
  • Well-structured
  • Thorough
  • Creative
  • Contribute to a good working environment
  • High work capacity
  • Strong work ethics

What we offer

  • Salary per annum depends on qualifications in a position as a postdoctoral research fellow (recent PhD graduates) or researcher (experienced applicants)
  • An exciting, translational project where your strong basic science background can directly benefit our sickest patients
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply?

If this sounds like you, please go ahead and apply – we look forward to hearing from you! Applications are done through the Oslo University Hospital recruitment system, more info here.

If you’d like to ask us anything before applying, please contact us.

Your application must include:

  • Cover letter (statement of motivation, summarising scientific work and research interest)
  • CV (summarising education, positions, pedagogical or administrative experience and other qualifying activity)
  • Copies of educational certificates (academic transcripts only)
  • List of publications
  • List of 3 reference persons (name, relation to candidate, e-mail and phone number). Please list both previous supervisors, peers (fellow postdocs/PhD students) and
    students that you have supervised.
 
Application deadline: 24.11.2023

Featured image credit: Oda Hveem (Visuello.)

Latest news

We presented two posters at the event.
Shiva's abstract was chosen for a talk in the oral communications session.
Oline's presentation was titled "CRISPR corrected T-cells for personalized therapy of IEIs."
Anniken will be working closely with Shiva and Frida on CRISPR gene editing of T cells.
We're excited to present our newest paper, currently in preprint!