Please note, application deadline has passed as of 31st May 2024.
Thank you to everyone who applied! Keep an eye out in the News for any future open positions in our group.
Our group is growing! We’re happy to announce an open post-doc position at our lab, focusing on single-cell sequencing of the CRISPR-corrected cells.
Please find the related information below, and get in touch if you’re interested in this position or would like any further details. 😊
About the position
This is a 2.5-year Postdoctoral Fellow position, part of the NORPOD program and a joint position between our lab at NCMM and the Kilpinen Lab at FIMM, requiring travel between the labs in Norway and Finland.
Our group focuses on building a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for monogenic immune diseases.
We use high-throughput biology techniques to optimise, develop and understand the CRISPR-Cas9 system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the gene editing technologies for the benefit of the patients in the Nordic hospitals.
NCMM was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway, and has altogether 11 research groups.
The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.
Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year.
The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence.
Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.
NORPOD is a collaborative postdoctoral program of the Nordic EMBL Partnership for Molecular Medicine. The partnership is a network of four national research centers across the Nordics and the European Molecular Biology Laboratory (EMBL), with complementary research expertise at the forefront of molecular medicine research. With the NORPOD program, the Nordic EMBL Partnership aims to foster the next generation of researchers in molecular medicine by implementing joint postdoctoral research projects to nurture strong competences and research excellence.
Work tasks
The project focuses on correcting immune cells from patients with diverse inborn errors of immunity using in-house CRISPR-Cas9 protocols at Haapaniemi lab. The cells will then be characterized with different Next Generation Sequencing methods including single cell sequencing to verify correction of the disease phenotype.
- Culture and transfect peripheral blood mononuclear cells and hematopoietic stem cells
- Run flow cytometry–based immunological assays
- Design high-throughput biology experiments on robotics platforms
- Prepare Next Generation Sequencing libraries and analyze resulting data
Required qualifications and skills
- PhD with at least one published first author paper
- Documented research experience in one or more of the following: Next Generation Sequencing & data analysis, immunology, genetics or stem cell biology
- Fluent oral and written English communication skills
The following qualifications will count in the assessment of the applicants:
- Experience with any of the following techniques: multi-color flow cytometry, immune cell culture and transfection, Next Generation Sequencing library preparation
- Experience in genetic analyses
- Python, Perl, R or other relevant programming language skills
Required personal skills:
- Organized, meticulous and independent
- Ability to communicate and work in shared multidisciplinary projects
- Willingness to supervise students and staff
How to apply?
If this sounds like you, please go ahead and apply – we look forward to hearing from you! Applications are done through Jobbnorge.
If you’d like to ask us anything before applying, please contact us.